Read the following and choose the option with incorrect statement.

(i) In E.coli the average rate of polymerization is 2000 bp per second.

(ii) The replication of DNA occur within a small opening of DNA helix, referred to as replication fork. The polymerization occur in one direction that is 3’5’.

(iii) The DNA replication in the template with 5’ 3’ polarity is discontinuous and the discontinuously synthesized fragment are joined by enzyme DNA ligase.

(iv) The process of copying genetic information from one strand of the DNA into RNA is termed as translation.

(v) A transcription unit in DNA is defined primarily by three regions in DNA: promoter, structural gene and terminator.

(vi) During transcription, the DNA strand having polarity 3’ 5’ is referred to as coding strand.

(vii) Coding strand of DNA is used as reference point while defining transcription and its polarity is 5’ 3’.

(viii) Promoter is a DNA sequence that provides binding site for RNA polymerase and is located down stream of coding strand.

(ix) Terminator is a DNA sequences that defines the end of the process of transcription and is located down stream of coding strand.

(x) In eukaryotes, the coding sequences are called exons that appears in mature RNA. They are interrupted by introns.

(xi) In bacteria, during transpiration RNA polymerase facilitates opening of the helix and continues elongation.

(xii) RNA polymers is associated transiently with ʻ ʼ which is called initiation factor and with ʻ ʼ which is called termination factor.

(xiii) In eukaryotes, RNA polymerase I transcribes mRNAs; RNA polymerase III transcribes tRNA, 5srRNA and snRNAs; and RNA polymerase II transcribes rRNA.

(xiv) Splicing is the process where exons are removed and introns are joined in a defined order.